台灣大學醫學系醫學士
台灣大學醫學院藥理學研究所博士

馬偕紀念醫院台北總院皮膚科住院醫師
馬偕紀念醫院新竹分院皮膚科主治醫師
馬偕紀念醫院台北總院皮膚科主治醫師

皮膚科學，藥理學

乾癬及發炎性疾病，皮膚藥理，細胞分化與死亡，中草藥及天然物，光生物學

1. Ching-Chi Chi, Yen-Wen Wu, Ting-Hsing Chao, Chih-Chiang Chen, Yi-Ju Chen, Hao-Min Cheng, Hsien-Yi Chiu, Yu-Wei Chiu, Wen-Hung Chung, Tsu-Yi Hsieh, Po-Hsun Huang, Yu-Huei Huang, Shang-Hung Lin, Tsung-Hsien Lin, Kwo-Chang Ueng, Chun-Chieh Wang, Yu-Chen Wang, Nan-Lin Wu,  Charles Jia-Yin Hou,  Tsen-Fang Tsai.  2022 Taiwanese Dermatological Association (TDA), Taiwanese Association for Psoriasis and Skin Immunology (TAPSI), and Taiwan Society of cardiology (TSOC) joint consensus recommendations for the management of psoriatic disease with attention to cardiovascular comorbidities.. Journal of the Formosan Medical Association. Vol.122-No.6:442-457. Jun. 2023. (SCI/SCIE)
2. Ya-Chu Tsai, Hsun-Hao Chang, Sheng-Chieh Chou, Thomas W Chu, Yu-Jou Hsu, Chien-Yu Hsiao, Yuan-Hsin Lo, Nan-Lin Wu, Der-Chen Chang, Chi-Feng Hung.  Evaluation of the Anti-Atopic Dermatitis Effects of α-Boswellic Acid on Tnf-α/Ifn-γ-Stimulated HaCat Cells and DNCB-Induced BALB/c Mice.. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Vol.23(17):e9863. Aug. 2022. (SCI/SCIE)
3. Pa-Fan Hsiao, Yi-Ting Huang, Po-Hsuan Lu, Ling-Ya Chiu, Tzu-Han Weng, Chi-Feng Hung, Nan-Lin Wu*.  Thioredoxin-interacting protein regulates keratinocyte differentiation: Implication of its role in psoriasis. FASEB JOURNAL. Vol.36(5):e22313. May. 2022. (SCI/SCIE)
4. Nan-Lin Wu, Duen-Yi Huang, Shie-Liang Hsieh, Yang-Shia Dai, Wan-Wan Lin.  Decoy receptor 3 is involved in epidermal keratinocyte commitment to terminal differentiation via EGFR and PKC activation. EXPERIMENTAL AND MOLECULAR MEDICINE. Vol.54(4):542-551. Apr. 2022. (SCI/SCIE)
5. Po-Hsuan Lu, Jen-Yu Wang, Ling-Ya Chiu, Yi-Ting Huang, Chi-Feng Hung, Nan-Lin Wu*.  Spleen tyrosine kinase regulates keratinocyte inflammasome activation and skin inflammation induced by UVB irradiation. Free Radical Biology and Medicine. Vol.180:121-133. Feb. 2022. (SCI/SCIE)
6. Te-An Lee, Yi-Ting Huang, Pa-Fan Hsiao, Ling-Ya Chiu, Schu-Rern Chern,  Nan-Lin Wu*.  Critical roles of irradiance in the regulation of UVB-induced inflammasome activation and skin inflammation in human skin keratinocytes. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY. Vol.226:e112373. Jan. 2022. (SCI/SCIE)
7. Kuan-Ming Chiu, Yen-Ling Hung, Su-Jane Wang, Yi-Ju Tsai, Nan-Lin Wu,  Cher-Wei Liang,  Der-Chen Chang, Chi-Feng Hung.  Anti-Allergic and Anti-Inflammatory Effects of Neferine on RBL-2H3 Cells.. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Vol.22(20):e10994. Oct. 2021. (SCI/SCIE)
8. Hsien-Yi Chiu, Ying-Ming Chiu, Nien-Feng Chang Liao, Ching-Chi Chi, Tsen-Fang Tsai, Chang-Yu Hsieh, Tsu-Yi Hsieh, Kuo-Lung Lai, Tsu-Man Chiu, Nan-Lin Wu, Rosaline Chung-Yee Hui, Chaw-Ning Lee, Ting-Shun Wang, Po-Hua Chen, Chao-Chun Yang, Yu-Huei Huang.  Predictors of hepatitis B and C virus reactivation in patients with psoriasis treated with biologic agents: a 9-year multicenter cohort study.. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY. Vol.85(2):337-344. Aug. 2021. (SCI/SCIE)
9. Chi-Jen Chang, Yen-Ling Hung, Ting-Chen Chen, Hsin-Ju Li, Yuan-Hsin Lo, Nan-Lin Wu, Der-Chen Chang,  Chi-Feng Hung.  Anti-Proliferative and Anti-Migratory Activities of Hispidulin on Human Melanoma A2058 Cells.. Biomolecules. Vol.11(7):e1039. Jul. 2021. (SCI/SCIE)
10. Tsen-Fang Tsai, Tsu-Yi Hsieh, Ching-Chi Chi, Chung-Tei Chou, Lin-Fen Hsieh, Hsin-Hua Chen, Rosaline Chung-Yee Hui, Chih-Hung Lee, Chin-Hsiu Liu, Hwa-Chang Liu, Kai-Jieh Yeo, Chun-Hsiung Chen,, Hung-An Chen, Ying-Chou Chen, Yi-Ju Chen, Hsien-Yi Chiu, Ji-Chen Ho, Yu-Huei Huang, Po-Ju Lai, Woan-Ruoh Lee, Hsien-Tzung Liao,  Shang-Hung Lin, Jui-Cheng Tseng, Ting-Shun Wang, Nan-Lin Wu, Deng-Ho Yang, Wen-Chan Tsai, James Cheng-Chung Wei.  Recommendations for psoriatic arthritis management: A joint position paper of the Taiwan Rheumatology Association and the Taiwanese Association for Psoriasis and Skin Immunology. Journal of the Formosan Medical Association. Vol.120(3):926-938. Mar. 2021. (SCI/SCIE)
11. Ling-Ya Chiu,  Nan-Lin Wu,  Chi-Feng Hung,  Péter Bai, Yang-Shia Dai, Wan-Wan Lin.  PARP-1 involves in UVB-induced inflammatory response in keratinocytes and skin injury via regulation of ROS-dependent EGFR transactivation and p38 signaling. FASEB JOURNAL. Vol.35(3):e21393. Mar. 2021. (SCI/SCIE)
12. Tom C Chan, Nan-Lin Wu, Lai-San Wong, Yung-Tsu Cho, Chin-Yi Yang, Yu Yu, Po-Ju Lai, Yun-Ting Chang, I-Hsin Shih, Chih-Hung Lee, Chia-Yu Chu.  Taiwanese Dermatological Association consensus for the management of atopic dermatitis: A 2020 update.. Journal of the Formosan Medical Association. Vol.120(1 Pt 2):429-442. Jan. 2021. (SCI/SCIE)
13. Thomas Chu, Nan-Lin Wu, Chien-Yu Hsiao, Hsin-Ju Li, Tung-Yi Lin, Cheng-Hung Ku, Chi-Feng Hung.  An isoflavone extract from soybean cake suppresses 2,4-dinitrochlorobenzene-induced contact dermatitis. JOURNAL OF ETHNOPHARMACOLOGY. Vol.263:e113037. Dec. 2020. (SCI/SCIE)
14. Ting-Kuo Chang, Yu-Han Wang, Shu-Jui Kuo, Shih-Wei Wang, Chun-Hao Tsai, Yi-Chin Fong,  Nan-Lin Wu, Shan-Chi Liu, Chih-Hsin Tang.  Apelin enhances IL-1β expression in human synovial fibroblasts by inhibiting miR-144-3p through the PI3K and ERK pathways.. Aging-US. Vol.12(10):9224-9239. May. 2020. (SCI/SCIE)
15. Jen-Yu Wang, Po-Hsuan Lu, Wan-Wan Lin, Yu-Hsuan Wei, Ling-Ya Chiu, Schu-Rern Chern, Chi-Feng Hung,  Nan-Lin Wu*.  Galectin-3 regulates UVB-induced inflammation in skin. JOURNAL OF DERMATOLOGICAL SCIENCE. Vol.98(2):119-127. May. 2020. (SCI/SCIE)
16. Duen-Yi Huang, Wei-Yu Chen, Chi-Long Chen,  Nan-Lin Wu, Wan-Wan Lin.  Synergistic Anti-Tumour Effect of Syk Inhibitor and Olaparib in Squamous Cell Carcinoma: Roles of Syk in EGFR Signalling and PARP1 Activation.. Cancers. Vol.12(2):e489. Feb. 2020. (SCI/SCIE)
17. Hsin-Ju Li,  Nan-Lin Wu, Chi-Ming Pu, Chien-Yu Hsiao, Der-Chen Chang, Chi-Feng Hung.  Chrysin alleviates imiquimod-induced psoriasis-like skin inflammation and reduces the release of CCL20 and antimicrobial peptides. Scientific Reports. Vol.10(1):e2932. Feb. 2020. (SCI/SCIE)
18. Hua-Ching Chang, Duen-Yi Huang, Nan-Lin Wu, Reiji Kannagi, Li-Fang Wang, Wan-Wan Lin.  BLIMP1 transcriptionally induced by EGFR activation and post-translationally regulated by proteasome and lysosome is involved in keratinocyte differentiation, migration and inflammation. JOURNAL OF DERMATOLOGICAL SCIENCE. Vol.92:151-161. Nov. 2018. (SCI/SCIE)
19. Hsin-Ju Li, Nan-Lin Wu, Gon-Ann Lee, Chi-Feng Hung.  The Therapeutic Potential and Molecular Mechanism of Isoflavone Extract against Psoriasis. Scientific Reports. Vol.8(1):e6335. Apr. 2018. (SCI/SCIE)
20. Nan-Lin Wu, Fu-Tong Liu.  The expression and function of galectins in skin physiology and pathology. Experimental Dermatology. Vol.27:217-226. Mar. 2018. (SCI)
21. Nan-Lin Wu, Chih-Jung Hsu, Fang-Ju Sun, Tsen-Fang Tsai.  Efficacy and safety of secukinumab in Taiwanese patients with moderate-to-severe plaque psoriasis: subanalysis from ERASURE phase III study.. Journal of Dermatology. Vol.44:1129-1137. Oct. 2017. (SCI)
22. Po-Hsuan Lu, Hsin-Ju Li, Hsun-Hsien Chang,  Nan-Lin Wu*, Chi-Feng Hung.  Gold nanoparticles induce cell death and suppress migration of melanoma cells. Journal of Nanoparticle Research. Vol.342:1-12. Oct. 2017. (SCI)
23. Chi-Feng Hung, Chien-Yu Hsiao, Wen-Hao Hsieh,  Hsin-Ju Li, Yi-Ju Tsai, Chun-Nan Lin, Nan-Lin Wu*.  18ß-glycyrrhetinic acid derivative promotes proliferation, migration and aquaporin-3 expression in human dermal fibroblasts. Plos one. Vol.12:1-14. Aug. 2017. (SCI)
24. Nan-Lin Wu, Te-An Lee, Sheng-Fen Wang,  Hsin-Ju Li, Hui-Ting Chen, Tun-Cheng Chien, Chieh-Chen Huang, Chi-Feng Hung.  Green fluorescent protein chromophore derivativesuppresses ultraviolet A-induced JNK-signalling and apoptosis in keratinocytes and adverse effects in zebrafish embryos. Experimental Dermatology. Vol.25:983-990. Dec. 2016. (SCI)
25. Cheng-Hua Huang, Hsin-Ju Li, Nan-Lin Wu, Chien-Yu Hsiao, Chun-Nan Lin, Hsun-Hsien Chang, Chi-Feng Hung.  Photoprotective Effects of Cycloheterophyllin against UVA-Induced Damage and Oxidative Stress in Human Dermal Fibroblasts. Plos ONE. Vol.11:16176-16176. Sep. 2016. (SCI)
26. Nan-Lin Wu, Duen-Yi Huang, Li-Fang Wang, Reiji Kannagi, Yu-Ching Fan, Wan-Wan Lin.  Spleen tyrosine kinase mediates EGFR signaling to regulate keratinocyte terminal differentiation.. Journal of Investigative Dermatology. Vol.136:192-201. Jan. 2016. (SCI)
27. Nan-Lin Wu, Duen-Yi Huang, Hsin-Ni Tsou, Ying-Cing Lin, Wan-Wan Lin.  Syk Mediates IL-17-Induced CCL20 Expression by Targeting Act1-Dependent K63-Linked Ubiquitination of TRAF6. Journal of Investigative Dermatology. Vol.135:490-498. Feb. 2015. (SCI)
28. Shih-Chia Liu, Chi Chen, Ching-Hu Chung, Po-Chuan Wang, Nan-Lin Wu, Jen-Kun Cheng, Yu-Wei Lai, Hui-Lung Sun, Chieh-Yu Peng, Chih-Hsin Tang, Shih-Wei Wang.  Inhibitory Effects of Butein on Cancer Metastasis and Bioenergetic Modulation. Journal of Agricultural and Food Chemistry. Vol.62:9107-9117. Aug. 2014. (SCI)
29. Nan-Lin Wu, Duen-Yi Huang, Shie-Liang Hsieh, Cheng-Hsiang Hsiao, Te-An Lee, Wan-Wan Lin.  EGFR-driven up-regulation of decoy receptor 3 in keratinocytes contributes to the pathogenesis of psoriasis. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. Vol.1832-No.10:1538-1548. Oct. 2013. (SCI)
30. Ching-Hu Chung, Chien-Hsin Chang, Shiou-Sheng Chen, Che-Jen Hsiao, Nan-Lin Wu, Yen-Ling Chen, Tur-Fu Huang, Po-Chuan Wang, Hung-I Yeh, Shih-Wei Wang, Hsueh-Hsiao Wang, Juei-Yu Yen.  Butein inhibits angiogenesis of human endothelial progenitor cells via the translation dependent signaling pathway. Evidence-Based Complementary and Alternative Medicine. Vol.2013:94318-94318. May. 2013. (SCI)
31. Nan-Lin Wu, Jia-You Fang, Marcelo Chen, Chia-Jung Wu, Chieh-Chen Huang, Chi-Feng Hung.  Chrysin Protects Epidermal Keratinocytes from UVA- and UVB-Induced Damage. Journal of Agricultural and Food Chemistry. Vol.59-No.15:8391-8400. Aug. 2011. (SCI)
32. Nan-Lin Wu, Te-An Lee, Te-Lung Tsai, Wan-Wan Lin.  TRAIL-induced keratinocyte differentiation requires caspase activation and p63 expression. Journal of Investigative Dermatology. Vol.131-No.4:874-883. Apr. 2011. (SCI)
33. Nan-Lin Wu, Yuh-Chiau Chiang, Chieh-Chen Huang, Jia-You Fang, Der-Fang Chen, Chi-Feng Hung.  Zeaxanthin inhibits PDGF-BB-induced migration in human dermal fibroblasts. Experimental Dermatology. Vol.19-No.8:173-181. Aug. 2010. (SCI)

1. Nan-Lin Wu*, Yi-Ting Huang,  Ling-Ya Chiu, Jen-Yu Wang.  Modulation of IL-36-triggered signaling in skin keratinocytes by AMPK. International Societies for Investigative Dermatology Meeting 2023 (ISID 2023). May. 2023.
2. Nan-Lin Wu*, Te-An Lee, Pa-Fan Hsiao, Ling-Ya Chiu, Schu-Rern Chern.  Irradiance Critically Modulates in UVB-elicited Inflammasome Activation in Human Skin Keratinocytes. 14th Asia Pacific Federation of Pharmacologists. Nov. 2021.
3. Pa-Fan Hsiao, Ling-Ya Chiu, Nan-Lin Wu*.  Thioredoxin-interacting protein regulates epidermal keratinocyte differentiation. The 1 5 th Annual Meeting of the Taiwanese Society for Investigative Dermatology. Nov. 2020.
4. Nan-Lin Wu*, Po-Hsuan Lu, Yu-Xuan Wei, Ling-Ya Chiu, Chi-Feng Hung.  Spleen tyrosine kinase mediates UVB-triggered inflammasome activation in epidermal keratinocytes.. The 44th Annular meeting of the Japanese Society for Investigative Dermatology, 2019. Nov. 2019.
5. Nan-Lin Wu*, Wan-Wan Lin, Pa-Fan Hsiao, Duen-Yi Huang, Schu-Rern Chern, Yu-Hsuan Wei, Chi-Feng Hung.  Galectin-3 regulates UVB-induced inflammation in skin.. International Investigative Dermatology 2018. May. 2018.
6. Nan-Lin Wu, Duen-Yi Huang, Shie-Liang Hsieh, Wan-Wan Lin.  Immunomodulator Decoy Receptor 3 Regulates the Terminal Differentiation of Human Epidermal Keratinocytes. 12th Annual Meeting of the Taiwanese Society for Investigative Dermatology. Nov. 2017.
7. Nan-Lin Wu, Duen-Yi Huang, Hsin-Ni Tsou, Wan-Wan Lin.  Regulatory roles of spleen tyrosine kinase (Syk) in IL-17-induced CCL20 expression in epidermal keratinocytes. 23rd 世界皮膚科大會. Jun. 2015.

台灣藥理學會--杜聰明博士研究生論文獎

旅遊，電影

t222@mmc.edu.tw

alvin.4200@mmh.org.tw