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馬偕醫學院 Mackay Medical College
師資陣容  
曾廣文
(Tseng, Kuang-Wen)
職稱 教授
主要學歷
  • 國立台灣大學解剖學及細胞生物學博士
  • 國立台灣大學解剖學及細胞生物學碩士
現職
  • 馬偕醫學院醫學系教授
教學專長
  • 解剖學、組織學、視覺細胞生物學、神經解剖學
研究專長
  • 神經退化、視覺科學
學術期刊
  1. Lin XJ, Zhao TB, Mei GP, Liu RX, Li CY, Wang XW, Qu ZX, Lin SD, Walkerf MJ, Yi XQ, Zhang PG, Tseng KW, Xu XM,  Lin CH, Sung G .  7,8-Dihydroxyflavone accelerates recovery of Brown-Sequard syndrome in adult female rats with spinal cord lateral hemisection. BIOMEDICINE & PHARMACOTHERAPY. Vol.153:e113397. Sep. 2022. (SCI/SCIE)
  2. Fu YS, Chen PR, Yeh CC, Pan JY, Kuo WC, Tseng KW*.  Human umbilical mesenchymal stem cell xenografts repair UV-Induced photokeratitis in a rat model. Biomedicines. Vol.10(5):e1125. May. 2022. (SCI/SCIE)
  3. Chen SJ, Lin TB, Peng HY, Lin CH, Lee AS, Liu HJ, Li CC, Tseng KW*.  Protective effects of fucoxanthin dampen pathogen-associated molecular pattern (PAMP) lipopolysaccharide-induced inflammatory action and elevated intraocular pressure by activating Nrf2 signaling and generating reactive oxygen species. Antioxidants. Vol.10-No.7:e1092-e1092. Jul. 2021. (SCI/SCIE)
  4. Sun G, Lin X,  Yi X, Zhang P, Liu R, Fu B, Sun Y,  Li J, Jiao S, Tian T, Xu XM, Tseng KW, Lin CH.  Aircraft noise, like heat stress, causes cognitive impairments via similar mechanisms in male mice. CHEMOSPHERE. Vol.274:e129739-e129739. Jul. 2021. (SCI/SCIE)
  5. Chen SJ, Lin TB, Peng HY, Liu HJ, Lee AS, Lin CH, Tseng KW*.  Cytoprotective Potential of Fucoxanthin in Oxidative Stress-Induced Age-Related Macular Degeneration and Retinal Pigment Epithelial Cell Senescence In Vivo and In Vitro. Marine Drugs. Vol.19(2):e0114-e0114. Feb. 2021. (SCI/SCIE)
  6. Hsieh MC, Ho YC, Lai CY, Wang HH, Yang PS, Cheng JK, Chen GD, Ng SC, Lee AS, Tseng KW, Lin TB, Lin TBHsieh MC, Ho YC, Lai CY, Wang HH, Yang PS, Cheng JK, Chen GD, Ng SC, Lee AS, Tseng KW, Lin TB, Peng HY., Peng HY.  Blocking the spinal Fbxo3/CARM1/K+ channel epigenetic silencing pathway as a strategy for neuropathic pain relief. Neurotherapeutics. Vol.2021:977-977. Jan. 2021. (SCI/SCIE)
  7. Yao HY, Tseng KW, Nguyen HT, Kuo CT, Wang HC.  Hyperspectral Ophthalmoscope Images for the Diagnosis of Diabetic Retinopathy Stage. Journal of Clinical Medicine. Vol.9(6):e1613-e1613. May. 2020. (SCI/SCIE)
  8. Tseng KW, Hsiao YP, Jen CP, Chang TS, Wang HC.  Cu2O/PEDOT:PSS/ZnO Nanocomposite Material Biosensor for Esophageal Cancer Detection. Sensors. Vol.20(9):E2455-E2455. Mar. 2020. (SCI/SCIE)
  9. Tseng KW,  Chen TH, Chen SJ, Su YD, Wang HC.  Laser Headlamp with a Tunable Light Field. Energies. Vol.12-No.4:707-712. Mar. 2019. (SCI/SCIE)
  10. Shiu-Jau Chen , Ching-Ju Lee, Tzer-Bin Lin, Hsien-Yu Peng , Hsiang-Jui Liu, Yu-Shan Chen, Kuang-Wen Tseng *.  Protective Effects of Fucoxanthin on Ultraviolet B-Induced Corneal Denervation and Inflammatory Pain in a Rat Model.. Marine Drugs. Vol.17-No.3:e152-e152. Mar. 2019. (SCI/SCIE)
  11. Fan YP,  Hsia CC, Tseng KW, Liao CK, Fu TW, Ko TL , Chiu MM, Shih YH, Huang PY, Chiang YC, Yang CC, Fu YS.  The therapeutic potential of human umbilical mesenchymal stem cells from Wharton's jelly in the treatment of rat peritoneal dialysis-induced fibrosis. Stem Cells Translational Medicine. Vol.5(2):235-247. Feb. 2016. (SCI/SCIE)
  12. Shiu-Jau Chen, Ching-Ju Lee, Tzer-Bin Lin, Hsiang-Jui Liu, Shuan-Yu Huang, Jia-Zeng Chen, Kuang-Wen Tseng*.  Inhibition of ultraviolet B-induced expression of the proinflammatory cytokines TNF-α and VEGF in the cornea by fucoxanthin treatment in a rat model. Marine Drugs. Vol.14-No.1:e13-e13. Jan. 2016. (SCI/SCIE)
  13. SJ Chen, CJ Lee, YC Wen, TB Lin, HY Peng, KW Tseng*.  Effects of UVB-induced damage on corneal tissues in surgical menopause female rats by bilaterally. Life Science Journal. Vol.11-No.5:428-433. Apr. 2014. (SCI)
  14. H-Y Li, CJ Lee, YC Wen, SJ Chen, KW Tseng*.  EGCG, a major polyphenol in green tea, protects human retinal pigment epithelium (ARPE-19) cells from. Life Science Journal. Vol.11-No.4:424-429. Apr. 2014. (SCI)
  15. Mei-Lin Peng, Ching-Ju Lee, Chung-Liang Chien, Chun-Lan Liu, Cheng-Yu Tsai, Kuang-Wen Tseng*.  Protective effects of (-)-epigallocatechin gallate on blue light-induced damage in retinoblastoma Y79 cells by activating estrogen receptor pathway. Life Science Journal. Vol.10-No.1:192-198. Jan. 2013. (SCI)
  16. Cheng HM, Sun HY, Lin DP, Chang HH, Chen ST, Yeh SM, Su KC, Tseng KW, Chen BY, Cheng CY.  Characterising visual deficits in children of an urban elementary school in Taiwan. Clin Exp Optom. Vol.95:531-537. Mar. 2012. (SCI)
  17. Peng ML, Tsai CY, Chien CL, Hsiao CJ, Tseng KW*.  The Influence of Low-powered Family LED Lighting on Eyes in Mice Experimental Model.. Life Science Journal. Vol.9-No.1:477-482. Feb. 2012. (SCI)
  18. Peng ML, Lee CJ, Haung SC, Tseng KW*.  Inhibition of neurite outgrowth and promotion of neuronal degeneration by the atropine in Neuro2a cells.. Life Science Journal. Vol.9-No.3:341-346. Feb. 2012. (SCI)
  19. Tseng KW, Peng ML, Wen YC, Liu KJ, Chien CL.  Neuronal Degeneration in autonomic nervous system of Dystonia musculorum mice. J Biomed Sci. Vol.18:9-23. Mar. 2011. (SCI)
  20. Li HY, Lin PC, Chen CY, Liao KK, Peng ML, Tseng KW*.  Sensory and Sympathetic Denervation in the Foot Pads of Mice with a Defect in Bullous Pemphigoid Antigen 1(BPAG1) gene.. Chung Shan Med J. Vol.21:189-199. Jul. 2010. (臺灣其它具同儕審核機制之期刊)
  21. Tseng KW*, Chau YP, Yang MF, Lu KS, Chien CL.  Abnormal cellular translocation of alpha-internexin in spinal motor neurons of Dystonia musculorum mice. The Journal of Comparative Neurology. Vol.507:1053-1064. Mar. 2008. (SCI)
  22. Tseng KW, Lu KS, Chien CL.  A possible cellular mechanism of neuronal loss in the dorsal root ganglia of Dystonia musculorum (dt) mice. J Neuropathol Exp Neurol. Vol.65:336-47. Dec. 2006. (SCI)
  23. Shih SC, Tseng KW, Lin SC, Kao CR, Chou SY, Wang HY, ChangWH, Chien CL.  Expression patterns of transforming growth factor-beta and its receptors in gastric mucosa of patients with refractory gastric ulcer. World J Gastroenterol. Vol.11:116-131. Dec. 2005. (SCI)
  24. Yen ML, Su JL, Chien CL, Tseng KW, Yang CY, ChenWF, Chang CC, Kuo ML.  Diosgenin induces hypoxia-inducible factor-1 activation and angiogenesis through estrogen receptor-related phosphatidylinositol3-kinase/Akt and p38 mitogen-activated protein kinase pathways in osteoblasts. Mol Pharmacol. Vol.68:1061-1073. Jun. 2005. (SCI)
  25. Juan SH, Lee TS, Tseng KW, Liou JY, , Shyue SK, Wu KK, Chau LY.  Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice. Circulation. Vol.104:1519-1525. Oct. 2001. (SCI)
  26. Shih SC, Chien CL, Tseng KW,  Lin SC, Kao CR.  Immunohistochemical studies of transforming growth factor-beta and its receptors in the gastric mucosa of patients with refractory gastric ulcer. J Formos Med Assoc. Vol.98:613-620. Oct. 1999. (SCI)
研討會
  1. 李景如, 陳佳增, 陳旭照, 曾廣文*。  Inhibition of UVB-induced keratitis and corneal edema by fucoxanthin. 中華民國解剖學學會教學學術研討會暨年度會員大會. 8月 2020.
  2. 曾廣文 *, 陳柏儒, 傅毓琇, 郭文娟。  Protective effects of human umbilical cord mesenchymal stem cells on UVB-induced photokeratitis. 解剖學學會會員大會暨學術研討會]. 8月 2020.
  3. 陳旭照, 曾廣文 *.  Protective effects of fucoxanthin on UVB-induced corneal denervation and inflammatory pain in a rat model. 第34屆天然藥物研討會. Oct. 2019.
  4. Tseng KW*.  Promising therapeutic methods in aging-related visual degeneration. Chia-ASEAN forum on aging and disease. Dec. 2018.
  5. TB Lin, ML Peng , CK Liao, YC Wen, KW Tseng*.  protective effects of fucoxanthin on selenite-inducedhuman RPE cells. 33rd JACBS. Mar. 2018.
  6. 曾廣文*.  Inhibition of UVB-induced Corneal edema by Fucoxanthin Treatment. 跨院際研討會. Nov. 2017.
  7. ML Peng , CJ Lee, KW Tseng*.  Protective effects of fucoxanthin on UV-induced denervation in cornea and dendritic spine instability in retina. 32rd JACBS. Mar. 2017.
  8. TB Lin.  Protective effects of fucoxanthin on UV-induced ocular damage in vivo and in vitro. 31rd JACBS. Mar. 2017.
  9. CK Liao, TL Ko , KW Tseng*.  Protective effects of EGCG against light-induced cell damage in retinoblastoma Y79 cells and human RPE cells. 30rd JACBS. Mar. 2016.
  10. HY Li, Liao CK, KW Tseng*.  EGCG protects against from blue light-induced retinoblastoma Y-79 cells degeneration. 30rd JACBS. Mar. 2016.
  11. C JLee, KW Tseng*.  Effect of atropine on nerve innervation in vivo. 29rd JACBS. Mar. 2015.
  12. DP Fu, YS Chen, KW Tseng*.  Protective effects of (-)-epigallocatechin gallate on free radical-induced retinal pigment epithelium cells disorders. 29rd JACBS. Mar. 2015.
  13. Tseng KW*, Wen YC, Liu KJ, Chien CL.  Neuronal degeneration in sympathetic and parasympathetic nervous system of BPAG1-defiency mice. The 26th Joint Annual Conference of Biomedical Science. Mar. 2012.
  14. Tsai CY, Wen YC, Lai ML, Tseng KW*.  The influence of low powered LED illumination in retinal photoreceptor. The 26th Joint Annual Conference of Biomedical Science. Mar. 2012.
  15. Lai ML, Chao CC, Chien CL, Tseng KW*.  Effect of atropine on nerve innervation in iris of mice.. The 26th Joint Annual Conference of Biomedical Science. Mar. 2012.
  16. Wen YC, Liu KJ, Tsai CY,  Tseng KW*.  Effect of atropine, a muscarinic cholinergic receptor antagonist on binocular responses and iris nerve innervation in mice. The 25th Joint Annual Conference of Biomedical Science. Mar. 2011.
  17. Wen JC, Lu KS, Tseng KW*.  Immunohistochemisty of study of sympathetic innerevation in Bullous Pemphigoid Antigen 1 (BPAG1) genedeficiency mice. The 25th Joint Annual Conference of Biomedical Science. Mar. 2011.
  18. Tseng KW,  Wen YJ, Chang CS, Lu KS , Chien CL.  Degeneration of Dorsal Root Ganglia and Spinal Motor Neurons in Dystonia musculorum Mice. The 24th Joint Annual Conference of Biomedical Science. Mar. 2010.
  19. Tseng KW, Chien CL.  Spinal motor neurons survive after abnormal cellular translocation of internexin in dystonia musculorum mice. 48th Annual Meeting of the American Society for Cell Biology in San Francisco. Dec. 2008.
計畫
計畫起訖年月計畫名稱擔任職務
2024-08~2025-07校外研究計畫獎助款(B)_MMC-RD-113-1B-P013_曾廣文主持人
2023-08~2024-07校外研究計畫獎助款(B)_MMC-RD-112-1B-P002_曾廣文主持人
2022-08~2023-07校外研究計畫獎助款(B)_MMC-RD-111-1B-P008_曾廣文主持人
2022-07~2023-02海洋褐藻活性成分對角膜損傷及異常翼狀贅片增生之保護作用-111年度科技部大專生研究計畫-護理學系三年級何旻璇主持人
2021-08~2022-07校外研究計畫獎助款(B)_MMC-RD-110-1B-P005_曾廣文主持人
2021-08~2022-07探索中醫藥黃耆對癌症轉移的影響與治療應用(II)-探討formononetin在角膜眼翳增生與角膜新生血管之作用機轉主持人
2021-07~2022-02探討以Exosome處理角膜炎及白內障之成效主持人
2021-07~2022-02探討褐藻素對於視力保健的功能:活體動物及細胞培養主持人
2020-08~2021-07校外研究計畫獎助款(B)_1091B05_曾廣文主持人
2020-01~2020-12探討海洋褐藻萃取物對於內毒素造成虹膜炎及虹膜神經退化的保護性功能主持人
2019-08~2020-07海藻植物萃取物褐藻素對於高齡老化相關視覺障礙參與的保護與修護功能主持人
2019-08~2021-07海藻植物萃取物褐藻素對於高齡老化相關視覺障礙參與的保護與修護功能主持人
2019-07~2020-06探討褐藻素對人類視網膜色素上皮細胞受氧化壓力誘發細胞傷害的保護作用-108年度校內大專生-護理學系李俊頡主持人
2019-01~2019-12探討海藻褐素對於神經性角膜炎與白內障疾病中的扮演保護與修護作用主持人
2018-08~2019-07校外研究計畫獎助款_曾廣文_1071B30主持人
2018-01~2018-12利用動物與細胞培養模式探討神經傳導阻斷藥物擬膽鹼素性拮抗劑對虹彩神經支配與瞳孔收縮的影響主持人
2017-08~2019-07探討海藻褐素對傷害性紫外線光線誘發眼角膜光傷害與三叉神經節組織 細胞疼痛信息之影響主持人
2017-08~2018-07校外研究計畫獎助款_曾廣文_1061B20主持人
2017-08~2020-07探討海藻褐素對傷害性紫外線光線誘發眼角膜光傷害與三叉神經節組織 細胞疼痛信息之影響主持人
2017-03~2017-07校外研究計畫獎助款_曾廣文_1052B01主持人
2015-08~2016-07探討海藻褐素反轉傷害性紫外線光線誘發眼角膜與視網膜之神經組織損傷退化之保護效果主持人
2015-08~2017-07探討海藻褐素反轉傷害性紫外線光線誘發眼角膜與視網膜之神經組織損傷退化之保護效果主持人
2014-08~2015-07探討海藻褐素對傷害性光線誘發眼球組織損傷退化之保護效果: 動物實驗模式及細胞培養模式研究主持人
2014-01~2014-12以小鼠動物模式探討神經傳導阻斷藥物擬膽鹼素性拮抗劑對虹彩神經支配的影響主持人
2012-01~2012-12居家 LED 照明燈源對眼睛潛藏傷害之研究主持人
2012-01~2013-06雌激素受體對於視網膜神經細胞的保護機制之探討其他
2008-08~2010-07中間絲蛋白堆積導致神經元退化之研究主持人
專書
出刊日期專書書名作者
2016-11眼球解剖生理學曾廣文;許又文;
2009-07眼解剖生理學曾廣文
組織
擔任期間機構職務
2013-07-01 ~
2014-07-31
眼視光學會常務理事
編審
期間期刊名稱性質
2020-11-27 ~
2020-11-27
pharmaceuticals審查委員
2020-04-22 ~
2020-04-22
microorganisms審查委員
2020-01-13 ~
2020-01-13
applsci審查委員
2019-11-27 ~
2019-11-27
pharmaceutics審查委員
2019-08-28 ~
2019-08-28
diagnostics審查委員
2019-07-15 ~
2019-07-15
International Journal of Environmental Research and Public Health審查委員
2018-06-08 ~
2018-06-08
marine drugs審查委員
2015-12-02 ~
2016-01-03
Oncotarget審查委員
聯絡方式

tseng@mmc.edu.tw

02-26360303#1227

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